Comparison of cytotoxicity of hydroxyurea in normal and rapidly proliferating epidermis and small intestine in mice.

Effects of capsaicin in low doses and high doses on the small intestine motor response in wild-type and TRPV1 knockout mice

Cytotoxicity assessment of nanoliposomal Paclitaxel and nanoliposomal Hydroxyurea in MCF-7 cells

Nanotechnology has revolutionized diagnosis and treatment of cancers. Breast cancer is oneof the most prevalent cancers among women. Paclitaxel and hydroxyurea are important drugsin treatment of breast cancer but their use is limited due to a series of significant side effects.On the other hand, nanoliposomes are widely used as nanocarriers for targeted drug delivery.In this study, cytotoxic ef...

مقـــایسه‌ی تاثیر عصاره‌ی زیره‌ی کــوهی منطقه‌ی یزد و نیکلوزاماید بر کرم هیمنولیپیس نـانـا

Background: Intestinal parasitic infections are a major health problem. Due to adverse effects of medicines this study was conducted to evaluate the in vitro and in vivo effects of Bunium Persicum (B.P) on Hymenolepis nana in comparison with niclosomide in albino mice in Ahvaz in 1996. Materials and Methods: In this experimental study at in vitro stage the effect of different concentrations of ...

Preparation and Evaluation of a Liposome Drug Delivery System in Cancer Treatment in vitro

Cancer is a fatal disease and relatively widespread in the world; Breast cancer is the most prevalent cancer among women. Hydroxyurea (HU) is a chemotherapy drug for the cure of cancer different types in patients, for example breast cancer, but has several defects, for to remove these problems in this study a nanoliposome (NL) suspension for Hydroxyurea (HU) delivery in breast cancer cell thera...

Melatonin Role in Ameliorating Radiation-induced Skin Damage: From Theory to Practice (A Review of Literature)

Normal skin is composed of epidermis and dermis. Skin is susceptible to radiation damage because it is a continuously renewing organ containing rapidly proliferating mature cells. Radiation burn is a damage to the skin or other biological tissues caused by exposure to radiofrequency energy or ionizing radiation. Acute skin reaction is the most frequently occurring side effect of radiation thera...